Acute Communicable
Disease Control

Contact Information
County of Los Angeles
Department of Public Health
Acute Communicable Disease Control
313 N. Figueroa Street, #212
Los Angeles, CA 90012
Phone: (213) 240-7941
Fax: (213) 482-4856

Call 211 For Information 24/7

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Acute Communicable Disease Control
Clostridium difficile

Clostridium difficile is a gram-positive, spore-forming bacillus that causes an infectious diarrhea. It is found in stool and can survive on surfaces for a long time. C. difficile can be transmitted in healthcare settings from person-to-person, or by a contaminated environment and/or patient care equipment. Some people may be asymptomatic carriers of C. difficile.

Use of antibiotics are the most important risk factor in developing C. difficile infection (CDI), as antibiotics disrupt the normal intestinal microbiome and allow C. difficile spores to release toxins that cause moderate-to severe symptoms. Advanced age, previous hospitalization, underlying disease severity, and gastric acid suppression are other risk factors.

CDI can be prevented within healthcare settings by ensuring effective infection control and antimicrobial stewardship programs.

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